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Dr. Hai-Fang LI

Dr. Haifang LI obtianed her Ph.D from Research Center for Eco-Environmental Science, Chinese Academy of Sciences at 2005. She was as postdoctoral in Department of Chemistry, Tsinghua University during 2005-2007, and then accepted as a engineer at 2007 and senior engineer at 2012 by Tsinghua University. She is the group leader the analysis service and research of mass spectrometry and sample pretreatment.

Contact: Analysis Center 

         Department of Chemistry

         Tsinghua University

         Beijing 100084


Tel/Fax: +86-10-62797463




1) Hui Chen, Haifang Li, Jin-Ming Lin*, Determination of ammonia in water based on chemiluminescence resonance energy transfer between peroxymonocarbonate and branched NaYF4:Yb3+/Er3+ nanoparticle, Anal. Chem., 2012, 84, 8871-8879.

2) Dan Gao, Haifang Li, Niejun Wang, Jin-Ming Lin, Evaluation of the absorption of methotrexate on cells and its cytotoxicity assay by using an integrated microfluidic device coupled to mass spectrometer, Anal. Chem., 2012, 84(21), 9230-9237.

3) Xuexia Lin, Hai-Fang Li, Xiangwei He, Yuki Hashi, Jin-Ming Lin, Zhihua Wang, Automated on-line solid phase extraction coupled with high performance liquid chromatography-mass spectrometry for determination ofdeca-bromodiphenyl ether in human serum, J. Sep. Sci., 2012, 35(19), 2553 -2558.

4) Guilan Huang, Hai-Fang Li*, Yuan Ma, Jin-Ming Lin*, A vortex solvent bar microextraction combined with gas chromatography–mass spectrometry for the determination of phthalate esters in various sample matrices, Talanta, 2012, 100, 64-70.

5) Jianmin Yang, Hai-Fang Li, Meilan Li, Jin-Ming Lin, Gas dispersion concentration of trace inorganic contaminants from fuel gas and analysis using head-column field-amplified sample stacking capillary electrophoresis, Analyst, 2012, 137 (16), 3710-3716.

6) Hui Chen, Ruibo Li, Haifang Li, Jin-Ming Lin, Plasmon-assisted enhancement of the ultraweak chemiluminescence using Cu/Ni metal nanoparticles, J. Phys. Chem. C, 2012, 116, 14796-14803.

7) Meilan Li, Jianmin Yang, Hai-Fang Li, Jin-Ming Lin, Determination of trace anions in liquefied petroleum gas using liquid absorption and electrokinetic migration for enrichment followed by ion chromatography, J. Sep. Sci., 2012, 35(10-11), 1365-1371.

8) Qian-Yun Zhang, Hai-Fang Li, Hui Chen, Zhen Lin, Jin-Ming Lin, Comparison of chemiluminescence enzyme immunoassay based on magnetic microparticles with traditional colorimetric ELISA for the detection of serum -fetoprotein, J. Pharm. Anal., 2012, 2(2), 130–135.

9) Yingying Geng, Mingyu Ding, Hui Chen, Hai-Fang Li, Jin-Ming Lin, Preparation of hydrophilic carbon-1 functionalized magnetic microspheres coated with chitosan and application in solid-phase extraction of bisphenol A in aqueous samples, Talanta, 2012, 89, 189-194.

10) Huibin Wei, Haifang Li, Sifeng Mao, Jin-Ming Lin, Cell signaling analysis by mass spectrometry under co-culture conditions on an integrated microfluidic device, Anal. Chem., 2011, 83 (24), 9306–9313.

11) Hongyun Yang, Haifang Li, Masahito Ito, Jin-Ming Lin , Guangsheng Guo, Mingyu Ding, Combination of dynamic hollow fiber liquid-phase microextraction with HPLC analysis for the determination of UV filters in cosmetic products, Science China, Chemistry, 2011, , 54(10), 1627-1634.

12) Ling Lin, Zhaoxin Gao, Huibin Wei, Haifang Li, Feng Wang, Jin-Ming Lin, Fabrication of a gel particle array in a microfluidic device for bioassays of protein and glucose in human urine samples, Biomicrofluidics, 2011, 5, 034112, 10pages.

13) Weili Wei, Qiushui Chen, Haifang Li, Jin-Ming Lin, Self-assemblies of single-walled carbon nanotubes through tunable tethering of pyrenes by dextrin for rapidly chiral sensing, International Journal of Analytical Chemistry, 2011, ID862692, 10Pages

14) Ting Fei, Haifang Li, Mingyu Ding, Masahito Ito, Jin-Ming Lin, Determination of parabens in cosmetic products by solid-phase microextraction of poly(ethylene glycol) diacrylate thin film on fibers and ultra high-speed liquid chromatography with diode array detector, J. Sep. Sci., 2011, 34(13), 1599-1606.

15) Hai-Fang Li, Yuan-Feng Pang, Jiang-Jiang Liu, Jin-Ming Lin, Suspending nanoliter droplet arrays for cell capture and copper ion stimulation, Sensors & Actuators: B. Chemical, 2011, 155, 415–421.

16) Qingzhong Feng, Haifang Li, Zhiyong Zhang, Jin-Ming Lin, Gold nanoparticles for enhanced chemiluminescence and determination of 2,4-dichlorophenol in environmental water samples, Analyst, 2011, 136 (10), 2156 – 2160.

17) Haifang Li, Qianyun Zhang, Jin-Ming Lin, Recent development of microfluidic device for clinic analytical chemistry, Sepu, 2011, 29(4), 284-292.

18) Huibin Wei, Haifang Li, Dan Gao, Jin-Ming Lin, Multi-channel microfluidic devices combined with electrospray ionization quadrupole time-of-flight mass spectrometry applied to the monitoring of glutamate release from neuronal cells, The Analyst, 2010, 135, 2043-2050.

19) Qin Xiao, Haifang Li, Jin-Ming Lin, Development of a highly sensitive magnetic particles-based chemiluminescence enzyme immunoassay for thyroid stimulating hormone and comparison with two other immunoassays, Clin. Chim. Acta, 2010, 411, 1151-1153.

20) Yan Liu, Haifang Li, Jinghua Zhang, Tsuneaki Maeda, Jin-Ming Lin, Triacontyl modified silica gel as a sorbent for the preconcentration of polycyclic aromatic hydrocarbons in aqueous samples prior to gas chromatographic-mass spectrometry determination, Chin. Chem. Lett., 2010, 21, 730-733.

21) Dan Gao, Jiang-Jiang Liu, Hui-Bin Wei, Hai-Fang Li, Guang-Sheng Guo, Jin-Ming Lin, A microfluidic approach for anticancer drug analysis based on hydrogel encapsulated tumor cells, Anal. Chim. Acta, 2010, 665, 7-14.

22) Dan Gao, Hai-Fang Li, Guang-Sheng Guo, Jin-Ming Lin, Magnetic bead based immunoassay for enumeration of CD4+ T lymphocytes on a microfluidic device, Talanta, 2010, 82, 528-533.

23) Hong Li, Haifang Li, Zhifeng Chen, Jin-Ming Lin, On-chip solid phase extraction coupled with electrophoresis using modified magnetic microspheres as stationary phase, Science in China B, 2009, 52(12), 2287-2294.

24) Huibin Wei, Haifang Li, Jin-Ming Lin, A microfluidic device combined with ESI-Q-TOF mass spectrometer applied to analyze herbicides on a single C30 bead, J. Chromatogr. A, 2009, 1216, 9134-42.

25) Qin Xiao, Haifang Li, Guomao Hu, Hongrui Wang, Zhenjia Li, Jin-Ming Lin, Development of a rapid and sensitive magnetic chemiluminescent enzyme immunoassay for detection of luteinizing hormone in human serum, Clin. Biochem., 2009, 42, 1461-1467.

26) Yuanfeng Pang, Jiangjiang Liu, Haifang Li, Jin-Ming Lin, A microchip to analyze single crystal growth and size-controllability, Science in China, B, 2009, 52(7), 1014-1020.

27) Jiangjiang Liu, Dan Gao, Hai-Fang Li, Jin-Ming Lin, Controlled photopolymerization of hydrogel microstructures inside microchannels for bioassays, Lab Chip, 2009, 9, 1301-1305.

28) Hai-Fang Li, Hulie Zeng, Zhifeng Chen, Jin-Ming Lin, Chip-based enantioselective open-tubular capillary electrochromatography using bovine serum albumin-gold nanoparticle conjugates as the stationary phase, Electrophoresis, 2009, 30(6), 1022-1029.

29) Ying Li, Yuki Hashi, Yan Liu, Hai-Fang Li, Jin-Ming Lin, Comparison and optimization of several pretreatment techniques for determination of decabrominated diphenyl ether in polymer sample by gas chromatography mass spectrometry, Anal. Sci., 2009, 25(4), 523-527.

30) Ying Li, Tianran Wang, Yuki Hashi, Haifang Li, Jin-Ming Lin Determination of brominated flame retardants in electrical and electronic equipments with microwave-assisted extraction and gas chromatography-mass spectrometry, Talanta, 2009, 78, 1429-1435.

31) Haifang Li, Jin-Ming Lin, Applications of microfluidic systems in environmental analysis, Anal. Bioanal. Chem., 2009, 393(2), 555-567.

32) Yan Liu, Haifang Li, Jin-Ming Lin, Magnetic solid-phase extraction based on octadecyl functionalization of monodisperse magnetic ferrite microspheres for the determination of polycyclic aromatic hydrocarbons in aqueous samples coupled with gas chromatography-mass spectrometry, Talanta, 2009, 77, 1037-1042.

33) Hai-Fang Li, Zhi-Feng Chen, Jin-Ming Lin, Optical fiber coupling of light-emitting diode induced fluorescence detection for microchip electrophoresis, Fenxi Huaxue, 2008, 36(11), 1587-1591.

34) Shu-Xuan Liang, Haifang Li, Jin-Ming Lin, Reaction mechanism of surfactant sensitized chemiluminescence of bis(2,4,6-trichlorophyenyl) oxalate and hydrogen peroxide induced by gold nanoparticles, Luminescence, 2008, 23, 381-385.

35) Tian-Bing Xin, Shu-Xuan Liang, Xu Wang, Haifang Li, Jin-Ming Lin, Determination of estradiol in human serum using magnetic particles-based chemiluminescence immunoassay, Anal. Chim. Acta, 2008, 627, 277-284.

36) Waraporn Som-aum, Haifang Li, Jiangjiang Liu, Jin-Ming Lin, Determination of arsenate by sorption preconcentration on polystyrene beads packed in a microfluidic device with chemiluminescence detection, Analyst, 2008, 133, 1169-1175.

37) Zhao-Xin Gao, Hai-Fang Li, Jiang-Jiang Liu, Jin-Ming Lin, A simple microfluidic chlorine gas sensor based on gas-liquid chemiluminescence of luminal-chlorine system, Anal. Chim. Acta, 2008, 622, 143-149.

38) Hai-Fang Li, Jiangjiang Liu, Zongwei Cai, Jin-Ming Lin, Coupling a microchip with electrospray ionization quadrupole time-of-flight mass spectrometer for peptide separation and identification, Electrophoresis, 2008, 29(8), 1889-1894.

39) Shoulian Wei, Jiesheng Lin, Haifang Li, Jin-Ming Lin, Separation of seven fluoroquinolones by microemulsion electrokinetic chromatography and application to ciprofloxacin, lomefloxacin determination in urine, J. Chromatogr. A, 2007, 1163, 333-336.

40) Hu-Lie Zeng, Haifang Li, Xu Wang, Jin-Ming Lin, Chiral separation of FITC-labeled amino acids with gel electrochromatography using a polydimethylsiloxane microfluidic device, J. Capill. Electrophor. Microchip Technol., 2007, 10(1-2), 19-24.

41) Ke Li, Haifang Li, Tsuneaki Maeda, Jin-Ming Lin, Solid-phase extraction with C30-bonded silica for analysis of polycyclic aromatic hydrocarbons in airborne particulate matters by gas chromatography-mass spectrometry, J. Chromatogr. A, 2007, 1154, 74-80.

42) Ru-Song Zhao, Jin-Peng Yuan, Hai-Fang Li, Xu Wang, Ting Jiang, Jin-Ming Lin, Nonequilibrium hollow-fiber liquid-phase microextraction with in situ derivatization for the measurement of triclosan in aqueous samples by gas chromatography-mass spectrometry, Anal. Bioanal. Chem., 2007, 387, 2911-2915.

43) Yufang Zheng, Haifang Li, Zhihong Guo, Jin-Ming Lin, Zongwei Cai, Chip-based CE coupled to a quadrupole TOF mass spectrometer for the analysis of a glycopeptide, Electrophoresis, 2007, 28(9), 1305-1311.

44) Jiangjiang Liu, Haifang Li, Jin-Ming Lin, Measurements of surface tension of organic solvents using a simple microfabricated chip, Anal. Chem., 2007, 79 (1), 371 -377.

45) Chao Tian, Haifang Li, Guanqun Song, Jin-Ming Lin, Monitoring and kinetics study of single particle on a simple microfluidic chip, Anal. Chem., 2006, 78, 6270-6274.

46) Hai-Fang Li, Zongwei Cai, Jin-Ming Lin, Separation of catecholamines by microchip electrophoresis with a simple integrated laser-induced fluorescence detector, Anal. Chim. Acta, 2006, 565, 183-189.

47) Hu-Lie Zeng, Hai-Fang Li, Xu Wang, Jin-Ming Lin, Development of a gel monolithic column polydimethylsiloxane microfluidic device for rapid electrophoresis separation, Talanta, 2006, 69(1), 226-231.

48) Hai-Fang Li, Jin-Ming Lin, Rong-Guo Su, Zong-Wei Cai, Katsumi Uchiyama, A polymeric master replication technology for mass fabrication of poly(dimethylsiloxane) microfluidic devices, Electrophoresis, 2005, 26, 1825-1833.

49) Hu-Lie Zeng, Hai-Fang Li, Jin-Ming Lin, Chiral separation of dansyl amino acids by PDMS microchip gel monolithcolumn electrochrography with γ-cyclodextrin bonded in polyacrylamide, Anal. Chim. Acta, 2005, 551, 1-8.

50) H.-F. Li, J.-M. Lin, R. Su, K. Uchiyama, T. Hobo, A compactly integrated laser-induced fluorescence detector for microchip electrophoresis, Electrophoresis, 2004, 25, 1907-1915.