The Second Symposium for Cell Analysis on Micro/Nanofluidics Enter >>


The Bio and Environmental Analytical Chemistry Group was established in July 2004. Our group includes two faculty members, three research assistants, 6 postdoctoral fellows, 12 doctoral students, 4 exchange doctoral student, 1 master students, and 2 exchange master students. Currently, the main research contents in our group are as follows: 1)  Cell culture and metabolite analysis on microfluidic chip combined with mass spectrometry; 2) Microfluidics for single cell analysis; 3) Microfluidic methods for microbial analysis for environmental and food safety; 4) Sample pretreatment and chromatographic analysis; 5) Development of new instruments and equipments.

Our group currently obtained the project funds from National Natural Science Foundation of China, National Key R&D Program of China, and the international cooperation research. Long-term cooperation with famous universities, research institutes and enterprises at home and abroad for the student education and to develop chemiluminescence immunoassay kits, microfluidic chip, analytical instruments, and complex sample pretreatment devices.

We have well equipped from Tsinghua University and some companies, including five mass spectrometers, three LC-MS, one GC-MS, one microchip-mass spectrometer (Cellent CM-MS) and two sets of flow injection chemiluminescence instruments. 

The Analysis Center, Biomedical Analysis Center, Laboratory Animal Research Center and other experimental platforms in Tsinghua University can service to any research groups. They  can provide high level analysis services for post-doctoral and postgraduate research.

We welcome the collaboratory from different research groups or companies. Each year, 2-3 postdoctoral fellows, 2-3 doctoral students (including the foreign students),  1-2 excellent visiting scholars, and 2 undergraduate graduates can be accepted to our group. At the same time, excellent graduate students of other group are welcome to participate in the research activities of the research group as guest students.

Recent Publications
Evaluation of the accumulation of disulfiram and its copper complex in A549 cells using mass spectrometry
Xinling Lu, BinXin Lin, Ning Xu, Hua Huang, Yong Wang * and Jin-Ming Lin *
Talanta, 2020, 211, 120732    FullText Link
Combination stiffness gradient with chemical stimulation directs glioma cells migration on microfluidic chip
Jinxin Dou, Sifeng Mao, Haifang Li*, Jin-Ming Lin*
Anal. Chem., 2020, 92, 892-898    FullText Link
Concentrating single cells in picoliter droplets for phospholipid profiling on a microfluidic system
Weifei Zhang, Nan Li, Ling Lin*, Qiushi Huang, Katsumi Uchiyama, Jin-Ming Lin*
Small, 2019, 1903402 (7 pages)    FullText Link
Single-cell identification by microfluidic-based in-situ extracting and online mass spectrometric analysis of phospholipids expression
Qiushi Huang#, Sifeng Mao#, Mashooq Khan, Weiwei Li, Qiang Zhang and Jin-Ming Lin*
Chem. Sci., 2020, 11, 253–256    FullText Link
Controllable synthesis of multi-compartmental particles from 3D Microfluidics
Zengnan Wu, Yajing Zheng, Ling Lin*, Sifeng Mao, Zenghe Li, and Jin-Ming Lin*
Angew. Chem. Int. Ed., 2019, 59, 2225-2229    FullText Link