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王 栩 教授

王 栩,博士,男,山东师范大学 教授,博士生导师(http://www.hxc.sdnu.edu.cn/show.jsp?urltype=news.NewsContentUrl&wbtreeid=1003&wbnewsid=1508)。

2000年7月于聊城大学化学化工学院获理学学士学位,2003年7月于山东师范大学化学化工与材料科学学院获理学硕士学位,2006年7月于中国科学院生态环境研究中心获环境科学博士学位,2006年7月至2008年6月在清华大学化学系从事博士后研究。2008年9月进入山东师范大学化学化工与材料科学学院工作。先后参与863、国家科技支撑计划等多项省部级课题研究。目前主持国家自然科学基金青年基金、山东省高等学校科技计划项目以及教育部博士点基金青年教师基金各1项,参与承担国家重大科学研究计划(973)1项、国家自然科学基金重点项目1项及山东省自然科学基金重点项目1项。

研究兴趣:光分析化学,发光探针合成及细胞成像。

论文:

1. Xu Wang, Juan Sun, Weihong Zhang, Xiaoxu Ma, Jianzheng Lv, and Bo Tang*, A Near-infrared Ratiometric Fluorescent Probe for Rapid and Highly Sensitive Imaging of Endogenous Hydrogen Sulfide in Living Cells, Chem. Sci., 2013, 4, 2551-2556

2. 王栩,赵谦,孙娟,吕建政,唐波*,细胞内活性小分子近红外荧光成像探针,化学进展,2013,25,179-191

3. Xu Wang, Yanqing Xia, Yuanyuan Liu, Wenxue Qi, Qianqian Sun, Qian Zhao, and Bo Tang*, Dual-Luminophore-Labled Gold Nanoparticles with Completely Resolved Emission for the Simultaneous Imaging of MMP-2 and MMP-7 in Living Cells under Single Wavelength Excitation, Chem. Eur. J., 2012, 18, 7189-7195

4. 王栩,齐文学,夏雁青,唐波*,氧化还原可逆荧光探针研究及其在细胞成像中的应用进展,分析化学,2012,40,1301-1308

5. Mei Xue, Xu Wang, Lili Duan, Wen Gao, Lifei Ji and Bo Tang, A new nanoprobe based on FRET between functional quantum dots and gold nanoparticles for Fluoride anion and its applications for biological imaging, Biosens. Bioelectron., 2012, 36, 168-173

6. Mei Xue, Xu Wang, Hui Wang, Dezhan Chen and Bo Tang, Hydrogen bond breakage by Fluoride anion in a simple CdTe quantum dot/Gold nanoparticle FRET system and its analytical application, Chem. Commun., 2011, 47, 4986-4988

7. Mei Xue, Xu Wang, Hui Wang, Bo Tang*, The preparation of glutathione-capped CdTe quantum dots and their use in imaging of cells, Talanta, 2011, 83, 1680-1686

8. Mei Xue, Xu Wang, Xiaohua Zhang, Linhai Zhuo and Bo Tang*, Study on the Photoluminescence Character of Water-Soluble CdSe Nanocrystals Under Ambient Conditions, J. Nanosci. Nanotechnol., 2011, 11(4), 3191-3199

9. Zhenzhen Chen, Qingling Li, Xu Wang, Zhiyuan Wang, Ruirui Zhang, Miao Yin, Lingling Yin, Kehua Xu, Bo Tang*, Potent Method for the Simultaneous Determination of Glutathione and Hydrogen Peroxide in Mitochondrial Compartments of Apoptotic Cells with Microchip Electrophoresis-Laser Induced Fluorescence, Anal. Chem., 2010, 82, 2006-2012

10. Hongmin Li, Qingling Li, Xu Wang, Kehua Xu, Zhenzhen Chen, Xiaocong Gong, Xin Liu, Lili Tong, Bo Tang*, Simultaneous Determination of Superoxide and Hydrogen Peroxide in Macrophage RAW 264.7 Cell Extracts by Microchip Electrophoresis with Laser-Induced Fluorescence Detection, Anal. Chem., 2009, 81, 2193-2198

11. Bo Tang*, Fabiao Yu, Ping Li, Lili Tong, Xia Duan, Ting Xie, Xu Wang, A Near-Infrared Neutral pH Fluorescent Probe for Monitoring Minor pH Changes: Imaging in Living HepG2 and HL-7702 Cells, J. Am. Chem. Soc., 2009, 131, 3016-3023

12. Jie Ding, Xu Wang, Lin-Hai Zhuo, Bo Tang*, Hierarchical assembly of CdTe nanotubes and nanowires at water-oil interface, J. Mater. Chem., 2009, 19, 3027-3032

13. Bo Tang,* Lingling Yin, Xu Wang, Zhenzhen Chen, Lili Tong, Kehua Xu, A Fast-Response, Highly Sensitive and Specific Organoselenium Fluorescent Probe for Thiols and Its Application in Bioimaging, Chem. Commun., 2009, 5293-5295

14. Xu Wang, Mei-Lin Liu, Xiang-Lei Cheng, Jin-Ming Lin*, Flow-based luminescence sensing methods for environmental water analysis, TRAC Trends in Anal. Chem., 2009, 28, 75-87

15. Qianyun Zhang, Xu Wang*, Zhenjia Li, Jin-Ming Lin*, Evaluation of α-fetoprotein (AFP) in human serum by chemiluminescence enzyme immunoassay with two different solid phases, Anal. Chim. Acta, 2009, 631, 212-217

16. Tianbing Xin, Xu Wang*, Hui Jin, Shuxuan Liang, Jin-Ming Lin*, Zhenjia Li, Development of magnetic particle-based chemiluminescence enzyme immunoassay for the detection of 17β-estradiol in environmental water, Appl. Biochem. Biotechnol., 2009, 158, 582-594

17. Xu Wang*, Qian-Yun Zhang, Zhen-Jia Li, Xi-Tang Ying, Jin-Ming Lin*,Development of high-performance immunomagnetic chemiluminescence enzyme immunoassay for α-fetoprotein (AFP) in human serum, Clin. Chim. Acta, 2008, 393, 90-94

18. Zhen Lin, Xu Wang*, Zhen-Jia Li, Shi-Qi Ren, Guo-Nan Chen, Xi-Tang Ying, Jin-Ming Lin*, Development of a sensitive, rapid, biotin-streptavidin based chemiluminescent enzyme immunoassay for human thyroid stimulating hormone, Talanta, 2008, 75, 965-972

19. Shiqi Ren, Xu Wang*, Zhen Lin, Zhenjia Li, Xitang Ying, Guonan Chen and Jin-Ming Lin*, Development of a high-throughput, indirect antibody immobilization format chemiluminescence enzyme immunoassay (CLEIA) for the determination of progesterone in human serum, Luminescence, 2008, 23, 175-181

20. 靳辉,王栩*,辛天兵,高鹏, ,林金明*,梁淑轩,微孔板化学发光酶免疫分析法定量检测肿瘤标志物CA72-4的方法学研究, 科学通报,2008, 53, 1538-1543

21. 任世奇,王栩*,胡国茂,李振甲,唐宝军,林金明,测定人血清中孕酮的微板式化学发光酶免疫分析法研究,分析化学,2008, 36, 729-734

22. Xu Wang, Jin-Ming Lin*, Xitang Ying, Evaluation of carbohydrate antigen 50 (CA50) in human serum using magnetic particle-based chemiluminescence enzyme immunoassay, Anal. Chim. Acta, 2007, 598, 261-267

23. Xu Wang, Hui Chen, Jin-Ming Lin*, Xitang Ying, Development of a highly sensitive and selective microplate chemiluminescence enzyme immunoassay for the determination of free thyroxine in human serum, Int. J. Bio. Sci., 2007, (3): 274-280

24. Xu Wang, Hu-Lie Zeng, Yanlin Wei, Jin-Ming Lin*, A reversible fluorescence sensor based on insoluble β-cyclodextrin polymer for direct determination of bisphenol A (BPA) in aqueous solutions, Sens. Actuators B: Chemical, 2006, 114, 565-572

25. Xu Wang, Hulie Zeng, Lixia Zhao, Jin-Ming Lin*, A reversible fluorescence sensor using pyrene/dimethyl β-cyclodextrin complex for selective determination of bisphenol A (BPA) in water, Anal. Chim. Acta, 2006, 556, 313-318

26. Xu Wang, Hulie Zeng, Lixia Zhao, Jin-Ming Lin*, A selective optical chemical sensor for 2,6-dinitrophenol in waters based on fluorescence quenchment of a novel functional polymer, Talanta, 2006, 70, 160-168

专利:

1) 林金明,王 栩,魏彦林,一种水样分配装置,中国实用新型专利:ZL 200420058384.4

2) 林金明,曾湖烈,赵利霞,王 栩,纳米金属手性识别固定相、手性分离色谱仪及制备方法,中国发明专利:ZL 200510126212.5

著 作:《化学发光免疫分析》,编著 林金明,赵利霞,王 栩,化学工业出版社,2008年3月。

获奖:林金明,应希堂,王 栩,肖勤,张倩云,林珍,“生物标记物的化学发光免疫分析新方法研究及其相关试剂盒的研制”,2009年“中国分析测试协会科学技术奖(CAIA 奖)”一等奖。